Metabolic effects of bariatric surgery on type 2 diabetes mellitus

Type 2 diabetes mellitus (T2D) develops in adulthood, and its exact etiology is still unknown. Obesity is major independent risk factor for T2D, as it is closely associated with insulin resistance. Bariatric surgery was initially used to induce weight loss in obese patients. However, it was observed that it also results in improvement in many comorbidities, including T2D. Curing diabetes cannot yet be considered a goal of bariatric surgery, but it is a serendipitous benefit. Mechanism of the effects of bariatric surgery on T2D was discussed in this review.