E-ISSN 2587-0610
Laparoscopic Endoscopic Surgical Science The efficacy of post-laparoscopic analgesia on chronic pain after cholecystectomy operation [Laparosc Endosc Surg Sci ]
Laparosc Endosc Surg Sci . 2023; 30(3): 119-124 | DOI: 10.14744/less.2023.04379

The efficacy of post-laparoscopic analgesia on chronic pain after cholecystectomy operation

Mehmet Fatih Erol1, Sinan Arıcı2, Korgün Ökmen3, Berkay Demir4, Mehmet Emrah Bayam1, Uğur Duman1, Belkız Aylu1, Muhammed Doğangün5, Deniz Tihan1
1Department of General Surgery, Bursa Training and Research Hospital, Bursa, Türkiye
2Department of General Surgery, Bursa Hayat Hospital, Bursa, Türkiye
3Department of Anesthesia and Reanimation, Bursa Training and Research Hospital, Bursa, Türkiye
4Department of General Surgery, Malatya Hulusi Efendi State Hospital, Malatya, Türkiye
5Department of General Surgery, Sakarya aining and Research Hospital, Sakarya, Türkiye

INTRODUCTION: It has been reported that chronic pain syndrome occurs with an incidence of up to 41%. In this study, it was aimed to reveal the effect of analgesia methods applied in patients who underwent laparoscopic cholecystectomy with the formation of neuropathic pain in the early and late post-operative period.
METHODS: A total of 246 individuals who had underwent laparoscopic cholecystectomy have been analyzed retrospectively. The patients were divided into two groups. In the first group of patients, 100 mg tramadol hydrochloride was administered intravenously at 12-h intervals for analgesia in the first 24 h post-operatively. In the second group, analgesia was provided by applying a post-operative quadratus lumborum block (QLB). The primary outcomes of the study were based on the Visual Analog Scale (VAS) score, leeds assessment of neuropathic symptoms and signs (LANSS) pain scale, and short form 36 (SF–36) rating scale and the secondary outcomes were based on post-operative time, analgesia method, and length of hospital stay.
RESULTS: When the VAS, SF–36, mental component score, and S–LANSS pre-operative values were compared, there was no statistical difference between the groups (p<0.05), while VAS, S–LANSS scores in the 6th month follow-up denoted significance, respectively, (p<0.001 and p=0.004). No correlation was found between gender (p=0.234), age (p=0.193), operation time (p=0.790), and S–LANSS scores, which are thought to be determining factors in the development of neuropathic pain. A negative correlation was detected between weight and S–LANSS scores (n=246, p=0.035, Pearson Rho: −0.135).
DISCUSSION AND CONCLUSION: Considering the results of this study, it can be said that QLB is an effective method for the occurrence of neuropathic pain in both early and late post-operative periods.

Keywords: Analgesia, Chronic pain syndrome, Neuropathic pain, Quadratus lumborum block

Mehmet Fatih Erol, Sinan Arıcı, Korgün Ökmen, Berkay Demir, Mehmet Emrah Bayam, Uğur Duman, Belkız Aylu, Muhammed Doğangün, Deniz Tihan. The efficacy of post-laparoscopic analgesia on chronic pain after cholecystectomy operation. Laparosc Endosc Surg Sci . 2023; 30(3): 119-124

Corresponding Author: Sinan Arıcı, Türkiye
Manuscript Language: English
LookUs & Online Makale