Endoscopic retrograde cholangiopancreatography (ERCP) is very important in the diagnosis and treatment of hepatopancreatic biliary diseases. This study shares 5.5 months of general surgical endoscopy unit experience. This study retrospectively evaluated clinical, medical, and radiological data of 213 patients with cholangitis who underwent ERCP between May 15, 2019, and January 1, 2020. Patients were 22 90 (average 53.2) years old, and there were 148 women (69%) and 65 men (31%). The most common indication was biliary obstruction and pancreatitis with fistula due to hydatid cyst surgery. The procedure time ranged from 20 min to 90 min (average, 37 min). Cannulation was done successfully in 203 patients (95%). Four of 10 patients who could not be cannulated were then cannulated with a precut technique, two of them underwent PTK, and three patients underwent open choledochal exploration. ES was performed in 203 patients, choledochal stone excision was performed in 164 patients, and stents were placed in 18 patients. After ERCP, 72 patients had hyperamylasemia that did not require treatment. Eighteen patients had acute pancreatitis, and they recovered within 3 days of medical treatment. Two patients had bleeding, which was stopped with adrenaline balloon. No mortality was recorded.Keywords: Cholangitis, ERCP; endoscopic sphincterectomy.